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Ligand-Dependent Effects of Methionine-8 Oxidation in Parathyroid Hormone Peptide Analogues
LA-PTH is a long-acting parathyroid hormone (PTH) peptide analogue in preclinical development for hypoparathyroidism (HP). Like native PTH, LA-PTH contains a methionine at position 8 (Met8) that is predicted to be critical for function. We assessed the impact of Met oxidation on the functional prope...
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| Pubblicato in: | Endocrinology |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7774776/ https://ncbi.nlm.nih.gov/pubmed/33242090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa216 |
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