Comparable Initial Engagement of Intracellular Signaling Pathways by Parathyroid Hormone Receptor Ligands Teriparatide, Abaloparatide, and Long‐Acting PTH

Multiple analogs of parathyroid hormone, all of which bind to the PTH/PTHrP receptor PTH1R, are used for patients with osteoporosis and hypoparathyroidism. Although ligands such as abaloparatide, teriparatide (hPTH 1‐34 [TPTD]), and long‐acting PTH (LA‐PTH) show distinct biologic effects with respec...

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Publicado en:JBMR Plus
Autores principales: Sato, Tadatoshi, Verma, Shiv, Khatri, Ashok, Dean, Thomas, Goransson, Olga, Gardella, Thomas J, Wein, Marc N
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8101618/
https://ncbi.nlm.nih.gov/pubmed/33977197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10441
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