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Widespread Transcriptional Readthrough Caused by Nab2 Depletion Leads to Chimeric Transcripts with Retained Introns
Nascent RNA sequencing has revealed that pre-mRNA splicing can occur shortly after introns emerge from RNA polymerase II (RNA Pol II). Differences in co-transcriptional splicing profiles suggest regulation by cis-and/or trans-acting factors. Here, we use single-molecule intron tracking (SMIT) to ide...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7774305/ https://ncbi.nlm.nih.gov/pubmed/33113357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108324 |
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