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Splicing and transcription touch base: co-transcriptional spliceosome assembly and function

Several macromolecular machines collaborate to produce eukaryotic messenger RNA. RNA polymerase II (Pol II) translocates along genes that are up to millions of base pairs in length and generates a flexible RNA copy of the DNA template. This nascent RNA harbours introns that are removed by the splice...

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Detalles Bibliográficos
Publicado en:Nat Rev Mol Cell Biol
Main Authors: Herzel, Lydia, Ottoz, Diana S. M., Alpert, Tara, Neugebauer, Karla M.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928008/
https://ncbi.nlm.nih.gov/pubmed/28792005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm.2017.63
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