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Splicing of nascent RNA coincides with intron exit from RNA polymerase II

Protein-coding genes in eukaryotes are transcribed by RNA polymerase II (Pol II) and introns are removed from pre-mRNA by the spliceosome. Understanding the time lag between Pol II progression and splicing could provide mechanistic insights into the regulation of gene expression. Here we present two...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Oesterreich, Fernando Carrillo, Herzel, Lydia, Straube, Korinna, Hujer, Katja, Howard, Jonathon, Neugebauer, Karla M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826323/
https://ncbi.nlm.nih.gov/pubmed/27020755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.045
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