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Long-read sequencing of nascent RNA reveals coupling among RNA processing events

Pre-mRNA splicing is accomplished by the spliceosome, a megadalton complex that assembles de novo on each intron. Because spliceosome assembly and catalysis occur cotranscriptionally, we hypothesized that introns are removed in the order of their transcription in genomes dominated by constitutive sp...

詳細記述

保存先:
書誌詳細
出版年:Genome Res
主要な著者: Herzel, Lydia, Straube, Korinna, Neugebauer, Karla M.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028129/
https://ncbi.nlm.nih.gov/pubmed/29903723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.232025.117
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