Targeted Apoptosis of Ductular Reactive Cells Reduces Hepatic Fibrosis in a Mouse Model of Cholestasis

BACKGROUND AND AIMS: In cholestatic liver diseases, ductular reactive (DR) cells extend into the hepatic parenchyma and promote inflammation and fibrosis. We have previously observed that multidrug-resistant 2 (Mdr2(−/−)) double knockout (DKO) mice lacking tumor necrosis factor–related apoptosis-ind...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hepatology
Prif Awduron: Azad, Adiba I., Krishnan, Anuradha, Troop, Leia, Li, Ying, Katsumi, Tomohiro, Pavelko, Kevin, Kostallari, Enis, Guicciardi, Maria Eugenia, Gores, Gregory J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774262/
https://ncbi.nlm.nih.gov/pubmed/32128842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31211
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg