Mitochondrial dysfunction in inflammatory bowel disease alters intestinal epithelial metabolism of hepatic acylcarnitines

As the interface between the gut microbiota and the mucosal immune system, there has been great interest in the maintenance of colonic epithelial integrity through mitochondrial oxidation of butyrate, a short-chain fatty acid produced by the gut microbiota. Herein, we showed that the intestinal epit...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Smith, Sarah A., Ogawa, Sayaka A., Chau, Lillian, Whelan, Kelly A., Hamilton, Kathryn E., Chen, Jie, Tan, Lu, Chen, Eric Z., Keilbaugh, Sue, Fogt, Franz, Bewtra, Meenakshi, Braun, Jonathan, Xavier, Ramnik J., Clish, Clary B., Slaff, Barry, Weljie, Aalim M., Bushman, Frederic D., Lewis, James D., Li, Hongzhe, Master, Stephen R., Bennett, Michael J., Nakagawa, Hiroshi, Wu, Gary D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773399/
https://ncbi.nlm.nih.gov/pubmed/33141762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133371
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