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A CD209 ligand and a sialidase inhibitor differentially modulate adipose tissue and liver macrophage populations and steatosis in mice on the Methionine and Choline-Deficient (MCD) diet

Non-alcoholic fatty liver disease (NAFLD) is associated with obesity and type 2 diabetes and is characterized by the accumulation of fat in the liver (steatosis). NAFLD can transition into non-alcoholic steatohepatitis (NASH), with liver cell injury, inflammation, and an increased risk of fibrosis....

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Veröffentlicht in:PLoS One
Hauptverfasser: Pilling, Darrell, Karhadkar, Tejas R., Gomer, Richard H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773271/
https://ncbi.nlm.nih.gov/pubmed/33378413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0244762
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