Φορτώνει......
Development of tumor-targeting IRE-1 inhibitors for B cell cancer therapy
The IRE-1 kinase/RNase splices the mRNA of the XBP-1 gene, resulting in the spliced XBP-1 (XBP-1s) mRNA that encodes the functional XBP-1s transcription factor that is critically important for the growth and survival of B-cell leukemia, lymphoma and multiple myeloma (MM). Several inhibitors targetin...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Cancer Ther |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7773214/ https://ncbi.nlm.nih.gov/pubmed/33051362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-20-0127 |
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