Modulation of Aub–TDRD interactions elucidates piRNA amplification and germplasm formation

Aub guided by piRNAs ensures genome integrity by cleaving retrotransposons, and genome propagation by trapping mRNAs to form the germplasm that instructs germ cell formation. Arginines at the N-terminus of Aub (Aub–NTRs) interact with Tudor and other Tudor domain–containing proteins (TDRDs). Aub–TDR...

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Dades bibliogràfiques
Publicat a:Life Sci Alliance
Autors principals: Vrettos, Nicholas, Maragkakis, Manolis, Alexiou, Panagiotis, Sgourdou, Paraskevi, Ibrahim, Fadia, Palmieri, Daniel, Kirino, Yohei, Mourelatos, Zissimos
Format: Artigo
Idioma:Inglês
Publicat: Life Science Alliance LLC 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7772777/
https://ncbi.nlm.nih.gov/pubmed/33376130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000912
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