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Ribothrypsis, a novel process of canonical mRNA decay, mediates ribosome-phased mRNA endonucleolysis

Messenger RNAs transmit the genetic information that dictates protein production, and are a nexus for numerous pathways that regulate gene expression. The prevailing view of canonical mRNA decay is that it is mediated by deadenylation and decapping followed by exonucleolysis from the 3′ and 5′ ends....

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Bibliografiske detaljer
Udgivet i:Nat Struct Mol Biol
Main Authors: Ibrahim, Fadia, Maragkakis, Manolis, Alexiou, Panagiotis, Mourelatos, Zissimos
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889319/
https://ncbi.nlm.nih.gov/pubmed/29507394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0042-8
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