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Identification of in vivo, conserved, TAF15 RNA binding sites reveals the impact of TAF15 on the neuronal transcriptome

RNA binding proteins (RBPs) have emerged as major causative agents of Amyotrophic Lateral Sclerosis (ALS). To investigate the function of TAF15, an RBP recently implicated in ALS, we explored its target RNA repertoire in normal human brain and mouse neurons. Coupling high-throughput sequencing of im...

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Detalhes bibliográficos
Main Authors: Ibrahim, Fadia, Maragkakis, Manolis, Alexiou, Panagiotis, Maronski, Margaret A., Dichter, Marc A., Mourelatos, Zissimos
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594071/
https://ncbi.nlm.nih.gov/pubmed/23416048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.01.021
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