Modulation of Aub–TDRD interactions elucidates piRNA amplification and germplasm formation

Aub guided by piRNAs ensures genome integrity by cleaving retrotransposons, and genome propagation by trapping mRNAs to form the germplasm that instructs germ cell formation. Arginines at the N-terminus of Aub (Aub–NTRs) interact with Tudor and other Tudor domain–containing proteins (TDRDs). Aub–TDR...

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Detalles Bibliográficos
Publicado en:Life Sci Alliance
Main Authors: Vrettos, Nicholas, Maragkakis, Manolis, Alexiou, Panagiotis, Sgourdou, Paraskevi, Ibrahim, Fadia, Palmieri, Daniel, Kirino, Yohei, Mourelatos, Zissimos
Formato: Artigo
Idioma:Inglês
Publicado: Life Science Alliance LLC 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7772777/
https://ncbi.nlm.nih.gov/pubmed/33376130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000912
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