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Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis

Germ cells implement elaborate mechanisms to protect their genetic material and to regulate gene expression during differentiation. Piwi proteins bind piRNAs, a class of small germline RNAs whose biogenesis and functions are still largely elusive. We employed high throughput sequencing after crossli...

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Detalhes bibliográficos
Main Authors: Vourekas, Anastassios, Zheng, Qi, Alexiou, Panagiotis, Maragkakis, Manolis, Kirino, Yohei, Gregory, Brian D., Mourelatos, Zissimos
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414646/
https://ncbi.nlm.nih.gov/pubmed/22842725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2347
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