The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing

Piwi–piRNA (Piwi-interacting RNA) ribonucleoproteins (piRNPs) enforce retrotransposon silencing, a function critical for preserving the genome integrity of germ cells. The molecular functions of most of the factors that have been genetically implicated in primary piRNA biogenesis are still elusive....

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Bibliographic Details
Published in:Genes Dev
Main Authors: Vourekas, Anastassios, Zheng, Ke, Fu, Qi, Maragkakis, Manolis, Alexiou, Panagiotis, Ma, Jing, Pillai, Ramesh S., Mourelatos, Zissimos, Wang, P. Jeremy
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2015
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378194/
https://ncbi.nlm.nih.gov/pubmed/25762440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.254631.114
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