A Mendelian randomization of γ′ and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke

Fibrinogen is a key component of the coagulation cascade, and variation in its circulating levels may contribute to thrombotic diseases, such as venous thromboembolism (VTE) and ischemic stroke. Gamma prime (γ′) fibrinogen is an isoform of fibrinogen that has anticoagulant properties. We applied 2-s...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Maners, Jillian, Gill, Dipender, Pankratz, Nathan, Laffan, Michael A., Wolberg, Alisa S., de Maat, Moniek P. M., Ligthart, Symen, Tang, Weihong, Ward-Caviness, Cavin K., Fornage, Myriam, Debette, Stephanie, Dichgans, Martin, McKnight, Barbara, Boerwinkle, Eric, Smith, Nicholas L., Morrison, Alanna C., Dehghan, Abbas, de Vries, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7770565/
https://ncbi.nlm.nih.gov/pubmed/33367543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019004781
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