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Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers
Immunodominance to nonneutralizing epitopes is a roadblock in designing vaccines against several diseases of high interest. One hypothetical possibility is that limited CD4 T cell help to B cells in a normal germinal center (GC) response results in selective recruitment of abundant, immunodominant B...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7769167/ https://ncbi.nlm.nih.gov/pubmed/33355623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201254 |
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