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Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers
Immunodominance to nonneutralizing epitopes is a roadblock in designing vaccines against several diseases of high interest. One hypothetical possibility is that limited CD4 T cell help to B cells in a normal germinal center (GC) response results in selective recruitment of abundant, immunodominant B...
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| Vydáno v: | J Exp Med |
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| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Rockefeller University Press
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7769167/ https://ncbi.nlm.nih.gov/pubmed/33355623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201254 |
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