Modulating the quantity of HIV Env-specific CD4 T cell help promotes rare B cell responses in germinal centers

Immunodominance to nonneutralizing epitopes is a roadblock in designing vaccines against several diseases of high interest. One hypothetical possibility is that limited CD4 T cell help to B cells in a normal germinal center (GC) response results in selective recruitment of abundant, immunodominant B...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Lee, Jeong Hyun, Hu, Joyce K., Georgeson, Erik, Nakao, Catherine, Groschel, Bettina, Dileepan, Thamotharampillai, Jenkins, Marc K., Seumois, Gregory, Vijayanand, Pandurangan, Schief, William R., Crotty, Shane
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7769167/
https://ncbi.nlm.nih.gov/pubmed/33355623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201254
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados