Chemical modification of pro-inflammatory proteins by peroxynitrite increases activation of TLR4 and NF-κB: Implications for the health effects of air pollution and oxidative stress

Environmental pollutants like fine particulate matter can cause adverse health effects through oxidative stress and inflammation. Reactive oxygen and nitrogen species (ROS/RNS) such as peroxynitrite can chemically modify proteins, but the effects of such modifications on the immune system and human...

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Publicado en:Redox Biol
Autores principales: Ziegler, Kira, Kunert, Anna T., Reinmuth-Selzle, Kathrin, Leifke, Anna Lena, Widera, Darius, Weller, Michael G., Schuppan, Detlef, Fröhlich-Nowoisky, Janine, Lucas, Kurt, Pöschl, Ulrich
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
Materias:
Articles from the Special Issue on Impact of environmental pollution and stress on redox signaling and oxidative stress pathways; Edited by Thomas Münzel and Andreas Daiber
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767743/
https://ncbi.nlm.nih.gov/pubmed/32739154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101581
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