Chemical modification of pro-inflammatory proteins by peroxynitrite increases activation of TLR4 and NF-κB: Implications for the health effects of air pollution and oxidative stress

Environmental pollutants like fine particulate matter can cause adverse health effects through oxidative stress and inflammation. Reactive oxygen and nitrogen species (ROS/RNS) such as peroxynitrite can chemically modify proteins, but the effects of such modifications on the immune system and human...

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Veröffentlicht in:Redox Biol
Hauptverfasser: Ziegler, Kira, Kunert, Anna T., Reinmuth-Selzle, Kathrin, Leifke, Anna Lena, Widera, Darius, Weller, Michael G., Schuppan, Detlef, Fröhlich-Nowoisky, Janine, Lucas, Kurt, Pöschl, Ulrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2020
Schlagworte:
Articles from the Special Issue on Impact of environmental pollution and stress on redox signaling and oxidative stress pathways; Edited by Thomas Münzel and Andreas Daiber
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767743/
https://ncbi.nlm.nih.gov/pubmed/32739154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101581
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