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Chemical modification of pro-inflammatory proteins by peroxynitrite increases activation of TLR4 and NF-κB: Implications for the health effects of air pollution and oxidative stress

Environmental pollutants like fine particulate matter can cause adverse health effects through oxidative stress and inflammation. Reactive oxygen and nitrogen species (ROS/RNS) such as peroxynitrite can chemically modify proteins, but the effects of such modifications on the immune system and human...

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Publicat a:Redox Biol
Autors principals: Ziegler, Kira, Kunert, Anna T., Reinmuth-Selzle, Kathrin, Leifke, Anna Lena, Widera, Darius, Weller, Michael G., Schuppan, Detlef, Fröhlich-Nowoisky, Janine, Lucas, Kurt, Pöschl, Ulrich
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767743/
https://ncbi.nlm.nih.gov/pubmed/32739154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101581
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