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Src/CK2/PTEN-Mediated GluN2B and CREB Dephosphorylations Regulate the Responsiveness to AMPA Receptor Antagonists in Chronic Epilepsy Rats

Both α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor (AMPAR) and N-methyl-D-aspartate receptor (NMDAR) have been reported as targets for treatment of epilepsy. To investigate the roles and interactions of AMPAR and NMDAR in ictogenesis of epileptic hippocampus, we analyzed AMPAR antago...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Ji-Eun, Lee, Duk-Shin, Park, Hana, Kang, Tae-Cheon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766850/
https://ncbi.nlm.nih.gov/pubmed/33348808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249633
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