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Role of Src Family Kinases in BDNF-Mediated Suppression of Cocaine-Seeking and Prevention of Cocaine-Induced ERK, GluN2A, and GluN2B Dephosphorylation in the Prelimbic Cortex

Models of relapse have demonstrated that neuroadaptations in reward circuits following cocaine self-administration (SA) underlie reinstatement of drug-seeking. Dysregulation of the pathway from the prelimbic (PrL) cortex to the nucleus accumbens is implicated in reinstatement. A single BDNF infusion...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Barry, Sarah M, McGinty, Jacqueline F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561338/
https://ncbi.nlm.nih.gov/pubmed/28585567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.114
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