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Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: analysis of single-cell GluN2 subunit deletion in vivo

During development there is an activity-dependent switch in synaptic NMDA receptor subunit composition from predominantly GluN2B to GluN2A, though the precise role of this switch remains unknown. By deleting GluN2 subunits in single neurons during synaptogenesis, we find both GluN2B and GluN2A suppr...

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Hlavní autoři: Gray, John A., Shi, Yun, Usui, Hiroshi, During, Matthew J., Sakimura, Kenji, Nicoll, Roger A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183990/
https://ncbi.nlm.nih.gov/pubmed/21943605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.08.007
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