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Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: analysis of single-cell GluN2 subunit deletion in vivo

During development there is an activity-dependent switch in synaptic NMDA receptor subunit composition from predominantly GluN2B to GluN2A, though the precise role of this switch remains unknown. By deleting GluN2 subunits in single neurons during synaptogenesis, we find both GluN2B and GluN2A suppr...

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Detalhes bibliográficos
Main Authors: Gray, John A., Shi, Yun, Usui, Hiroshi, During, Matthew J., Sakimura, Kenji, Nicoll, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183990/
https://ncbi.nlm.nih.gov/pubmed/21943605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.08.007
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