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Potentiation of Synaptic AMPA Receptors Induced by the Deletion of NMDA Receptors Requires the GluA2 Subunit

Deletion of N-methyl-d-aspartate receptors (NMDARs) early in development results in an increase in the number of synaptic AMPA receptors (AMPARs), suggesting a role for NMDARs in negatively regulating AMPAR trafficking at developing synapses. Substantial evidence has shown that AMPAR subunits functi...

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Detalhes bibliográficos
Main Authors: Lu, Wei, Gray, John A., Granger, Adam J., During, Matthew J., Nicoll, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059181/
https://ncbi.nlm.nih.gov/pubmed/20980546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00725.2010
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