The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis

OBJECTIVE: Hypothalamic agouti-related peptide (AgRP) and pro-opiomelanocortin (POMC) expressing neurons play critical roles in control of energy balance. Glutamatergic input via n-methyl-d-aspartate receptors (NMDARs) is pivotal for regulation of neuronal activity and is required in AgRP neurons fo...

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Publicat a:Mol Metab
Autors principals: Üner, Aykut, Gonçalves, Gabriel H.M., Li, Wenjing, Porceban, Matheus, Caron, Nicole, Schönke, Milena, Delpire, Eric, Sakimura, Kenji, Bjørbæk, Christian
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588453/
https://ncbi.nlm.nih.gov/pubmed/26500840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.06.010
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