Axitinib in Ponatinib-Resistant B-Cell Acute Lymphoblastic Leukemia Harboring a T315L Mutation

Adult acute lymphoblastic leukemia (ALL) with BCR-ABL1 rearrangement (Philadelphia chromosome, Ph) is a hematological aggressive disease with a fatal outcome in more than 50% of cases. Tyrosine kinase inhibitors (TKIs) targeting the activity of BCR-ABL1 protein have improved the prognosis; however,...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Giudice, Valentina, Ghelli Luserna di Rorà, Andrea, Serio, Bianca, Guariglia, Roberto, Giannini, Maria Benedetta, Ferrari, Anna, Simonetti, Giorgia, Selleri, Carmine, Martinelli, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
Assuntos:
Case Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765866/
https://ncbi.nlm.nih.gov/pubmed/33419251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249724
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