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Anti-leukemic activity of axitinib against cells harboring the BCR-ABL T315I point mutation

The BCR-ABL; breakpoint cluster region-Abelson point mutation T315I is resistant to ABL tyrosine kinase inhibitors. However, axitinib, a vascular endothelial growth factor receptor inhibitor, is effective against this mutation. In this study, we investigated axitinib activity against ponatinib-resis...

詳細記述

保存先:
書誌詳細
出版年:J Hematol Oncol
主要な著者: Okabe, Seiichi, Tauchi, Tetsuzo, Tanaka, Yuko, Sakuta, Juri, Ohyashiki, Kazuma
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523922/
https://ncbi.nlm.nih.gov/pubmed/26239229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0190-9
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