The balance between mitotic death and mitotic slippage in acute leukemia: a new therapeutic window?

Mitosis is the process whereby an eukaryotic cell divides into two identical copies. Different multiprotein complexes are involved in the fine regulation of cell division, including the mitotic promoting factor and the anaphase promoting complex. Prolonged mitosis can result in cellular division, ce...

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Bibliographic Details
Published in:J Hematol Oncol
Main Authors: Ghelli Luserna di Rorà, Andrea, Martinelli, Giovanni, Simonetti, Giorgia
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880427/
https://ncbi.nlm.nih.gov/pubmed/31771633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0808-4
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