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A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target

The inhibition of the DNA damage response (DDR) pathway in the treatment of cancer has recently gained interest, and different DDR inhibitors have been developed. Among them, the most promising ones target the WEE1 kinase family, which has a crucial role in cell cycle regulation and DNA damage ident...

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Bibliografische gegevens
Gepubliceerd in:J Hematol Oncol
Hoofdauteurs: Ghelli Luserna di Rorà, Andrea, Cerchione, Claudio, Martinelli, Giovanni, Simonetti, Giorgia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507691/
https://ncbi.nlm.nih.gov/pubmed/32958072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00959-2
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