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Pixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions

Pixantrone is a novel aza-anthracenedione active against aggressive lymphoma and is being evaluated for use against various hematologic and solid tumors. The drug is an analog of mitoxantrone, but displays less cardiotoxicity than mitoxantrone or the more commonly used doxorubicin. Although pixantro...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Beeharry, Neil, Di Rora, Andrea Ghelli Luserna, Smith, Mitchell R, Yen, Timothy J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621998/
https://ncbi.nlm.nih.gov/pubmed/26177126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1070979
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