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Pixantrone induces cell death through mitotic perturbations and subsequent aberrant cell divisions

Pixantrone is a novel aza-anthracenedione active against aggressive lymphoma and is being evaluated for use against various hematologic and solid tumors. The drug is an analog of mitoxantrone, but displays less cardiotoxicity than mitoxantrone or the more commonly used doxorubicin. Although pixantro...

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Bibliografische gegevens
Gepubliceerd in:Cancer Biol Ther
Hoofdauteurs: Beeharry, Neil, Di Rora, Andrea Ghelli Luserna, Smith, Mitchell R, Yen, Timothy J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621998/
https://ncbi.nlm.nih.gov/pubmed/26177126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1070979
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