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Germline TP53 Testing in Breast Cancers: Why, When and How?

SIMPLE SUMMARY: TP53 variants detected in blood represent a main genetic cause of breast cancers occurring before 31 years of age. TP53 being included in most of the cancer gene panels, patients with breast cancer are offered germline TP53 testing, independently of the age of tumour onset and famili...

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Podrobná bibliografie
Vydáno v:Cancers (Basel)
Hlavní autoři: Evans, D. Gareth, Woodward, Emma R., Bajalica-Lagercrantz, Svetlana, Oliveira, Carla, Frebourg, Thierry
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764913/
https://ncbi.nlm.nih.gov/pubmed/33327514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123762
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