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Germline TP53 Testing in Breast Cancers: Why, When and How?

SIMPLE SUMMARY: TP53 variants detected in blood represent a main genetic cause of breast cancers occurring before 31 years of age. TP53 being included in most of the cancer gene panels, patients with breast cancer are offered germline TP53 testing, independently of the age of tumour onset and famili...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Evans, D. Gareth, Woodward, Emma R., Bajalica-Lagercrantz, Svetlana, Oliveira, Carla, Frebourg, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764913/
https://ncbi.nlm.nih.gov/pubmed/33327514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123762
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