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Germline TP53 Testing in Breast Cancers: Why, When and How?

SIMPLE SUMMARY: TP53 variants detected in blood represent a main genetic cause of breast cancers occurring before 31 years of age. TP53 being included in most of the cancer gene panels, patients with breast cancer are offered germline TP53 testing, independently of the age of tumour onset and famili...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Evans, D. Gareth, Woodward, Emma R., Bajalica-Lagercrantz, Svetlana, Oliveira, Carla, Frebourg, Thierry
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764913/
https://ncbi.nlm.nih.gov/pubmed/33327514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123762
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