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Toward Mechanistic Design of Surrogate Buffers for Dissolution Testing of pH-Dependent Drug Delivery Systems

The in vivo dissolution of enteric-coated (EC) products is often overestimated by compendial in vitro dissolution experiments. It is of great interest to mimic the in vivo conditions as closely as possible in vitro in order to predict the in vivo behavior of EC dosage forms. The reason behind this i...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Blechar, Johannes Andreas, Al-Gousous, Jozef, Wilhelmy, Christoph, Postina, Annika Marielina, Getto, Marcus, Langguth, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764239/
https://ncbi.nlm.nih.gov/pubmed/33321933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121197
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