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Toward Mechanistic Design of Surrogate Buffers for Dissolution Testing of pH-Dependent Drug Delivery Systems

The in vivo dissolution of enteric-coated (EC) products is often overestimated by compendial in vitro dissolution experiments. It is of great interest to mimic the in vivo conditions as closely as possible in vitro in order to predict the in vivo behavior of EC dosage forms. The reason behind this i...

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Détails bibliographiques
Publié dans:Pharmaceutics
Auteurs principaux: Blechar, Johannes Andreas, Al-Gousous, Jozef, Wilhelmy, Christoph, Postina, Annika Marielina, Getto, Marcus, Langguth, Peter
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764239/
https://ncbi.nlm.nih.gov/pubmed/33321933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121197
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