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Toward Mechanistic Design of Surrogate Buffers for Dissolution Testing of pH-Dependent Drug Delivery Systems

The in vivo dissolution of enteric-coated (EC) products is often overestimated by compendial in vitro dissolution experiments. It is of great interest to mimic the in vivo conditions as closely as possible in vitro in order to predict the in vivo behavior of EC dosage forms. The reason behind this i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Blechar, Johannes Andreas, Al-Gousous, Jozef, Wilhelmy, Christoph, Postina, Annika Marielina, Getto, Marcus, Langguth, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764239/
https://ncbi.nlm.nih.gov/pubmed/33321933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12121197
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