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Enzymatic Hydroxylation and Excision of Extended 5-Methylcytosine Analogues
Methylation of cytosine to 5-methylcytosine (mC) is a prevalent reversible epigenetic mark in vertebrates established by DNA methyltransferases (MTases); the methylation mark can be actively erased via a multi-step demethylation mechanism involving oxidation by Ten-eleven translocation (TET) enzyme...
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| Veröffentlicht in: | J Mol Biol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7763475/ https://ncbi.nlm.nih.gov/pubmed/33065111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.10.011 |
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