Enzymatic Hydroxylation and Excision of Extended 5-Methylcytosine Analogues

Methylation of cytosine to 5-methylcytosine (mC) is a prevalent reversible epigenetic mark in vertebrates established by DNA methyltransferases (MTases); the methylation mark can be actively erased via a multi-step demethylation mechanism involving oxidation by Ten-eleven translocation (TET) enzyme...

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Bibliographic Details
Published in:J Mol Biol
Main Authors: Tomkuvienė, Miglė, Ikasalaitė, Diana, Slyvka, Anton, Rukšėnaitė, Audronė, Ravichandran, Mirunalini, Jurkowski, Tomasz P., Bochtler, Matthias, Klimašauskas, Saulius
Format: Artigo
Language:Inglês
Published: Elsevier 2020
Subjects:
Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763475/
https://ncbi.nlm.nih.gov/pubmed/33065111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.10.011
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