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Methylarginine metabolites are associated with attenuated muscle protein synthesis in cancer-associated muscle wasting
Cancer cachexia is characterized by reductions in peripheral lean muscle mass. Prior studies have primarily focused on increased protein breakdown as the driver of cancer-associated muscle wasting. Therapeutic interventions targeting catabolic pathways have, however, largely failed to preserve muscl...
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| Izdano u: | J Biol Chem |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7762938/ https://ncbi.nlm.nih.gov/pubmed/33453990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014884 |
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