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The wasting-associated metabolite succinate disrupts myogenesis and impairs skeletal muscle regeneration
BACKGROUND: Muscle wasting is a debilitating co-morbidity affecting most advanced cancer patients. Alongside enhanced muscle catabolism, defects in muscle repair/regeneration contribute to cancer-associated wasting. Among the factors implicated in suppression of muscle regeneration are cytokines tha...
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| Udgivet i: | JCSM Rapid Commun |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7470228/ https://ncbi.nlm.nih.gov/pubmed/32905522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rco2.14 |
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