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The Role of Systemic Inflammation in Cancer-Associated Muscle Wasting and Rationale for Exercise as a Therapeutic Intervention

Progressive skeletal muscle wasting in cancer cachexia involves a process of dysregulated protein synthesis and breakdown. This catabolism may be the result of mal-nutrition, and an upregulation of both pro-inflammatory cytokines and the ubiquitin proteasome pathway (UPP), which can subsequently inc...

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Bibliografische gegevens
Gepubliceerd in:JCSM Clin Rep
Hoofdauteurs: Cole, Calvin L., Kleckner, Ian R., Jatoi, Aminah, Schwarz, Edward M., Dunne, Richard F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6534125/
https://ncbi.nlm.nih.gov/pubmed/31134216
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