Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood–brain barrier

Disruption of blood–brain barrier (BBB) integrity is a feature of various neurological disorders. Here we found that the BBB is differently affected during the preclinical, progression and remission phase of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS)....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zeitelhofer, Manuel, Adzemovic, Milena Z., Moessinger, Christine, Stefanitsch, Christina, Strell, Carina, Muhl, Lars, Brundin, Lou, Fredriksson, Linda, Olsson, Tomas, Eriksson, Ulf, Nilsson, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759579/
https://ncbi.nlm.nih.gov/pubmed/33361796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79598-z
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