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Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with unknown origins. Neurodegeneration in ALS mouse models occurs together with signs of disrupted blood–spinal cord barrier (BSCB) and regressed capillary network, but the molecular pathways contributing to these vascular pat...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Acta Neuropathol
Päätekijät: Lewandowski, Sebastian A., Nilsson, Ingrid, Fredriksson, Linda, Lönnerberg, Peter, Muhl, Lars, Zeitelhofer, Manuel, Adzemovic, Milena Z., Nichterwitz, Susanne, Lawrence, Daniel A., Hedlund, Eva, Eriksson, Ulf
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839168/
https://ncbi.nlm.nih.gov/pubmed/26687981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1520-2
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