Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with unknown origins. Neurodegeneration in ALS mouse models occurs together with signs of disrupted blood–spinal cord barrier (BSCB) and regressed capillary network, but the molecular pathways contributing to these vascular pat...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Lewandowski, Sebastian A., Nilsson, Ingrid, Fredriksson, Linda, Lönnerberg, Peter, Muhl, Lars, Zeitelhofer, Manuel, Adzemovic, Milena Z., Nichterwitz, Susanne, Lawrence, Daniel A., Hedlund, Eva, Eriksson, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839168/
https://ncbi.nlm.nih.gov/pubmed/26687981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1520-2
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