Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with unknown origins. Neurodegeneration in ALS mouse models occurs together with signs of disrupted blood–spinal cord barrier (BSCB) and regressed capillary network, but the molecular pathways contributing to these vascular pat...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol
Autors principals: Lewandowski, Sebastian A., Nilsson, Ingrid, Fredriksson, Linda, Lönnerberg, Peter, Muhl, Lars, Zeitelhofer, Manuel, Adzemovic, Milena Z., Nichterwitz, Susanne, Lawrence, Daniel A., Hedlund, Eva, Eriksson, Ulf
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839168/
https://ncbi.nlm.nih.gov/pubmed/26687981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1520-2
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