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Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with unknown origins. Neurodegeneration in ALS mouse models occurs together with signs of disrupted blood–spinal cord barrier (BSCB) and regressed capillary network, but the molecular pathways contributing to these vascular pat...
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| Publicado no: | Acta Neuropathol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4839168/ https://ncbi.nlm.nih.gov/pubmed/26687981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1520-2 |
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