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Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood–brain barrier

Disruption of blood–brain barrier (BBB) integrity is a feature of various neurological disorders. Here we found that the BBB is differently affected during the preclinical, progression and remission phase of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS)....

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Zeitelhofer, Manuel, Adzemovic, Milena Z., Moessinger, Christine, Stefanitsch, Christina, Strell, Carina, Muhl, Lars, Brundin, Lou, Fredriksson, Linda, Olsson, Tomas, Eriksson, Ulf, Nilsson, Ingrid
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759579/
https://ncbi.nlm.nih.gov/pubmed/33361796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79598-z
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