Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood–brain barrier

Disruption of blood–brain barrier (BBB) integrity is a feature of various neurological disorders. Here we found that the BBB is differently affected during the preclinical, progression and remission phase of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS)....

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zeitelhofer, Manuel, Adzemovic, Milena Z., Moessinger, Christine, Stefanitsch, Christina, Strell, Carina, Muhl, Lars, Brundin, Lou, Fredriksson, Linda, Olsson, Tomas, Eriksson, Ulf, Nilsson, Ingrid
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7759579/
https://ncbi.nlm.nih.gov/pubmed/33361796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79598-z
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