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The hedgehog co-receptor BOC differentially regulates SHH signaling during craniofacial development
The Hedgehog (HH) pathway controls multiple aspects of craniofacial development. HH ligands signal through the canonical receptor PTCH1, and three co-receptors: GAS1, CDON and BOC. Together, these co-receptors are required during embryogenesis to mediate proper HH signaling. Here, we investigated th...
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| Veröffentlicht in: | Development |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7758635/ https://ncbi.nlm.nih.gov/pubmed/33060130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.189076 |
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