Heat stress activates YAP/TAZ to induce the heat shock transcriptome

The Hippo pathway plays critical roles in cell growth, differentiation, organ development, and tissue homeostasis whereas its dysregulation can lead to tumorigenesis. YAP/TAZ are transcription co-activators and represent the main downstream effectors of the Hippo pathway. Here we show that heat stre...

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Vydáno v:Nat Cell Biol
Hlavní autoři: Luo, Min, Meng, Zhipeng, Moroishi, Toshiro, Lin, Kimberly C., Shen, Guobo, Mo, Fei, Shao, Bin, Wei, Xiawei, Zhang, Ping, Wei, Yuquan, Guan, Kun-Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757600/
https://ncbi.nlm.nih.gov/pubmed/33199845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-00602-9
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