The evolution of factor XI and the kallikrein-kinin system

Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of t...

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Gardado en:
Detalles Bibliográficos
Publicado en:Blood Adv
Main Authors: Ponczek, Michał B., Shamanaev, Aleksandr, LaPlace, Alec, Dickeson, S. Kent, Srivastava, Priyanka, Sun, Mao-fu, Gruber, Andras, Kastrup, Christian, Emsley, Jonas, Gailani, David
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2020
Assuntos:
Thrombosis and Hemostasis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7757006/
https://ncbi.nlm.nih.gov/pubmed/33351111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002456
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